How the hormonal changes of puberty impact lupus
Lupus in childhood usually attacks children as they enter puberty. Hormones change in an orderly pattern during puberty, making the study of lupus in this period of life ideal to understand how hormones affect autoimmunity and disease activity in lupus. Dr. Kathleen O'Neil received a Lupus Foundation of America national research program grant to support a multi-center longitudinal observational study of girls with prepubertal onset lupus as they approach and pass through puberty, measuring hormone levels, autoantibodies and markers of lupus activity.
In this video, Dr. O'Neil discusses the objectives of the study, the potential benefits to our understanding of lupus, and how in the future the disease might be treated and controlled in children.