Are antifungal treatments safe for people with lupus?

Lupus Foundation of America

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There are different types of fungal infections, and different types of treatments for these infections. Some of these treatments are not recommended for people with lupus. If you have lupus, it is important to always speak with your doctor about your treatment options, risks and benefits before taking an antifungal. Together, you and your doctor can determine the best strategy to treat your fungal infection.

Is Lamisil® safe for people with lupus?

In general, Lamisil® (terbinafine hydrochloride) therapy, used to treat fungal infections, should not be taken by people with lupus. Studies have found that this medication may cause or worsen cutaneous lupus symptoms or flares. In some isolated cases, this medication has also been known to cause or worsen systemic lupus symptoms, so, whenever possible, Lamisil ® should also be avoided by people with systemic lupus erythematosus. People with lupus should weigh their options and discuss possible risks with their doctor before initiating therapy.

Several other antifungals carry similar risk warnings, including potentially bringing on, or worsening, lupus symptoms. It is  important to speak with your rheumatologist prior to initiating any anti-fungal treatment.

Medically reviewed on